What happens if you take too many Huanglian Shangqing tablets?

Nov 06, 2025 Source: Cainiu Health
Dr. Yang Ziqi
Introduction
Taking excessive amounts of Huanglian Shangqing tablets may lead to various physical discomforts, primarily manifested as gastrointestinal damage, increased burden on the liver and kidneys, neurological abnormalities, electrolyte imbalances, and worsened allergic reactions. Huanglian Shangqing tablets should be taken strictly according to the instructions or medical advice; dosage should not be increased or duration of use extended without authorization. If significant discomfort occurs during medication, the drug should be discontinued promptly and appropriate symptomatic management undertaken.

Overconsumption of Huanglian Shangqing Tablets can lead to various physical discomforts, primarily manifested as gastrointestinal damage, increased burden on the liver and kidneys, neurological abnormalities, electrolyte imbalances, and exacerbated allergic reactions. The specific analysis is as follows:

1. Gastrointestinal Damage: The medication contains cold-natured ingredients such as rhubarb and Coptis (Huanglian). Excessive intake may irritate the gastrointestinal mucosa, causing symptoms like nausea, vomiting, abdominal pain, and diarrhea. In severe cases, watery stools or gastrointestinal bleeding may occur. Individuals with weak spleen and stomach functions are particularly susceptible, and long-term overuse may lead to gastrointestinal dysfunction.

2. Increased Liver and Kidney Burden: Drug metabolism primarily occurs in the liver and kidneys. Overdosing exceeds the metabolic capacity of these organs, increasing the risk of liver and kidney damage. This may result in elevated transaminase levels or abnormal kidney function indicators. Prolonged abuse could cause irreversible impairment of liver and kidney function.

3. Neurological Abnormalities: Excessive intake may affect central nervous system function, leading to dizziness, headache, insomnia, and irritability. Some individuals may also experience difficulty concentrating or limb numbness, which are related to overstimulation by the drug's components.

4. Electrolyte Imbalance: Frequent diarrhea caused by the drug can result in significant loss of body fluids and electrolytes, leading to fatigue, dry mouth, dizziness, and electrolyte disturbances. Severe cases may involve hypokalemia (low potassium) or hyponatremia (low sodium), affecting normal heart and muscle function.

5. Worsened Allergic Reactions: A small number of people are sensitive to the drug’s ingredients. While mild skin itching may occur at normal doses, excessive intake can intensify allergic reactions, resulting in widespread rashes, throat discomfort, breathing difficulties, and other serious symptoms that may endanger health.

Huanglian Shangqing Tablets should be taken strictly according to the instructions or medical advice. Do not increase the dosage or prolong usage duration without guidance. If significant discomfort occurs during use, discontinue the medication promptly and seek appropriate symptomatic treatment. Maintain a light diet during treatment, avoid concomitant use with other cold-natured medications, and minimize additional bodily stress.