What are the precautions for using ibuprofen suspension?

Generally, the main precautions for using ibuprofen suspension include adjusting the dosage according to age and weight, avoiding overdose or long-term use, contraindication for those with allergies, cautious use in patients with gastrointestinal disorders, and not taking it concurrently with similar antipyretic medications. If discomfort occurs after taking the medication, it is recommended to discontinue use promptly and seek medical advice. The detailed analysis is as follows:

1. Adjust dosage based on age and weight

Ibuprofen suspension dosage must be determined according to the user's age and body weight, as children of different ages have varying metabolic capacities. Insufficient dosage may fail to relieve symptoms, while excessive dosage can increase the burden on the liver and kidneys. For example, children aged 1–3 years usually take about 4 mL per dose. Dosage should strictly follow the instructions on the product label or medical advice and should not be adjusted arbitrarily.

2. Avoid overdose or prolonged use

This medication should not be used for more than 3 days to reduce fever or more than 5 days for pain relief. Overuse or extended use inhibits prostaglandin synthesis, which may cause gastrointestinal damage and lead to abnormal liver or kidney function. If symptoms persist, medical attention should be sought promptly; do not extend the duration of use without medical guidance.

3. Contraindicated for individuals with known allergies

Ibuprofen and other nonsteroidal anti-inflammatory drugs (NSAIDs) are contraindicated in individuals with known allergies. Allergic reactions may involve abnormal activation of the immune system, manifesting as rash, itching, difficulty breathing, and in severe cases, anaphylactic shock, which can be life-threatening.

4. Use with caution in patients with gastrointestinal diseases

Patients with gastrointestinal conditions such as gastric or duodenal ulcers should use this medication cautiously. Ibuprofen can irritate the gastric mucosa, potentially worsening mucosal damage and leading to symptoms such as stomach pain or bleeding. These patients should only use the drug if a physician determines that the benefits outweigh the risks.

5. Do not combine with similar antipyretic or analgesic drugs

Do not take ibuprofen together with other antipyretics or pain relievers such as acetaminophen (paracetamol) or diclofenac sodium. Since these drugs have similar mechanisms of action, combining them increases the risk of adverse effects—such as gastrointestinal bleeding or liver injury—without enhancing therapeutic efficacy, thereby posing unnecessary health risks.

During treatment, it is important to drink plenty of fluids to aid heat dissipation and drug metabolism. If symptoms such as vomiting, abdominal pain, or rash occur after taking the medication, stop using it immediately and consult a doctor. Store the medication out of reach of children to prevent accidental ingestion. Shake the bottle well before each use to ensure accurate dosing.