Can azithromycin and Sanjin tablets be taken together?

Nov 06, 2025 Source: Cainiu Health
Dr. Yang Ziqi
Introduction
Concurrent use as directed by a physician is commonly indicated for urinary tract infections caused by susceptible bacteria (such as bacterial urethritis, cystitis). Sanjin tablets, a traditional Chinese medicine, are often used to relieve urinary discomfort symptoms including frequent urination, urgency, and dysuria. If a susceptible bacterial infection is confirmed through examination, combining with azithromycin can inhibit bacterial proliferation and control the source of infection.

Generally speaking, whether azithromycin and Sanjin tablets can be taken together depends on the specific condition. They may be taken concurrently under medical guidance when treating urinary system diseases complicated by susceptible bacterial infections; however, concurrent use is not recommended in the absence of bacterial infection or for non-urinary conditions. If in doubt, it is advisable to consult a healthcare provider in advance. Detailed analysis is as follows:

Circumstances where concurrent use under medical supervision is appropriate typically involve urinary tract infections caused by susceptible bacteria (e.g., bacterial urethritis, cystitis). As a traditional Chinese medicine, Sanjin tablets are commonly used to relieve urinary symptoms such as frequent urination, urgency, and pain during urination. When diagnostic tests confirm a susceptible bacterial infection, combining azithromycin can help suppress bacterial growth and control the source of infection. The two medications target symptoms and underlying causes respectively, with no significant interaction in their mechanisms of action, thus working synergistically to improve the condition.

Concurrent use is generally not recommended in cases of non-bacterial urinary discomfort (e.g., urethral syndrome, viral urinary tract infections), as azithromycin would be ineffective. In such cases, Sanjin tablets alone may be sufficient to manage symptoms. Taking both drugs together unnecessarily increases drug intake, potentially worsening gastrointestinal side effects (such as nausea and bloating) or placing additional metabolic burden on the liver and kidneys. For infections in other areas, such as respiratory or skin infections, Sanjin tablets have no relevant therapeutic effect and therefore should not be combined with azithromycin.

When taking both medications, dosages should be carefully followed according to medical advice or product instructions. It is advisable to take them 30 minutes apart to minimize gastrointestinal irritation. During treatment, drink plenty of warm water and monitor whether symptoms improve.

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