What medication is good for regulating high blood lipid levels?

Generally, when medication is required to manage hyperlipidemia, appropriate drugs should be selected under medical guidance based on the specific type of lipid abnormality. Commonly used medications include atorvastatin calcium tablets, rosuvastatin calcium tablets, fenofibrate capsules, ezetimibe tablets, and probucol tablets. A detailed analysis is as follows:

1. Atorvastatin Calcium Tablets

This medication belongs to the statin class and works by inhibiting the activity of cholesterol-synthesizing enzymes in the liver, thereby reducing cholesterol production. It can also mildly lower triglyceride levels and increase high-density lipoprotein (HDL) cholesterol. It is suitable for patients with hypercholesterolemia and mixed hyperlipidemia, and helps slow the progression of atherosclerosis.

2. Rosuvastatin Calcium Tablets

Also a statin-class drug, it has a potent lipid-lowering effect and effectively reduces total cholesterol and low-density lipoprotein (LDL) cholesterol, with moderate effects on triglycerides. It is ideal for patients with hypercholesterolemia whose condition is not adequately controlled by diet, especially those requiring strong lipid-lowering therapy.

3. Fenofibrate Capsules

This is a fibrate-class medication that primarily activates peroxisome proliferator-activated receptor alpha (PPAR-α), promoting the breakdown and metabolism of triglycerides, thus lowering triglyceride levels. It can also slightly increase HDL cholesterol. It is indicated for hypertriglyceridemia and mixed hyperlipidemia characterized by elevated triglycerides.

4. Ezetimibe Tablets

Ezetimibe reduces blood cholesterol levels by inhibiting intestinal absorption of cholesterol. When used in combination with statins, it enhances overall lipid-lowering efficacy. It is suitable for patients with hypercholesterolemia not sufficiently controlled by diet alone, or for those who cannot tolerate high-dose statin therapy.

5. Probucol Tablets

This drug lowers total cholesterol and LDL cholesterol and possesses antioxidant properties that help inhibit the formation and progression of atherosclerotic plaques. It is used in the treatment of hypercholesterolemia, particularly beneficial for patients with familial hypercholesterolemia.

During treatment, regular monitoring of lipid levels, liver function, and creatine kinase is necessary, along with observation of any bodily reactions. Patients should also adopt a low-fat diet, reduce intake of animal offal and fried foods, increase consumption of vegetables, fruits, and whole grains, and engage in regular physical activity to help maintain optimal lipid control.