Is it normal for urea levels to be low in pregnant women?

Nov 11, 2025 Source: Cainiu Health
Dr. Zhang Lu
Introduction
In general, whether low urea levels in pregnant women are normal depends on the specific causes and clinical manifestations. After detecting low urea levels, one should first review recent dietary patterns, appropriately increase intake of high-quality protein, and reduce excessive fluid intake. Kidney and liver function should be regularly rechecked to monitor changes in relevant indicators. If any discomfort symptoms occur, prompt medical evaluation is necessary to determine the presence of underlying diseases.

In general, whether low urea levels in pregnant women are normal depends on the specific causes and clinical manifestations. The detailed analysis is as follows:

If a pregnant woman has low urea levels due to insufficient protein intake during pregnancy, excessive water consumption leading to urine dilution, or increased blood volume during pregnancy causing a relative decrease in urea concentration—and if there are no clinical symptoms such as fatigue, edema, or appetite abnormalities—this is usually considered normal. Such physiological decreases are often related to metabolic changes during pregnancy. Adjusting the diet and moderately controlling fluid intake can gradually restore urea levels, with no adverse effects on maternal or fetal health.

However, if low urea levels result from impaired liver function reducing urea synthesis, or kidney dysfunction affecting urea excretion, and are accompanied by symptoms such as fatigue, jaundice, or reduced urine output, this indicates an abnormal condition. Such pathological decreases suggest underlying diseases. Without timely intervention, these may affect nutrient supply and organ function during pregnancy, necessitating further tests to identify the root cause.

Upon detecting low urea levels, it's important to review recent dietary habits, increase intake of high-quality proteins appropriately, and reduce excessive fluid intake. Regular re-evaluation of kidney and liver function should be performed to monitor changes in laboratory values. If any discomfort or symptoms occur, prompt medical consultation is necessary to rule out underlying diseases and prevent treatment delays. Maintaining a balanced diet in daily life, avoiding extreme dieting or monotonous eating patterns, helps ensure adequate nutrition throughout pregnancy.