Is it still effective to use promestriene after three years of menopause?

Generally, if genitourinary atrophy symptoms are present three years after menopause and there are no contraindications to medication, Progynova (progestogen) may be effective. However, if such symptoms are absent or there are contraindications such as hormone-dependent diseases, it is ineffective and not recommended. If in doubt, it is advised to consult a healthcare provider in advance. Detailed analysis is as follows:

If vaginal dryness, dyspareunia (pain during intercourse), urinary frequency, urgency, or other genitourinary atrophy symptoms occur three years after menopause, and examinations show no contraindications such as hormone-sensitive tumors (e.g., breast cancer, endometrial cancer) or severe liver disease, using Progynova can provide local estrogen supplementation, improve mucosal atrophy, and relieve discomfort. In such cases, the treatment may be effective, but must be used strictly according to medical instructions.

If there are no genitourinary symptoms three years after menopause, there is no need to use this medication for symptom improvement. Using it unnecessarily will not yield significant benefits and may increase exposure to unnecessary hormonal risks. If contraindications such as hormone-dependent diseases or history of thrombosis exist, even if related symptoms are present, using this drug may worsen the condition. In these situations, it is ineffective and strictly prohibited.

Prior to using Progynova, a comprehensive medical evaluation by a physician is required to determine whether the patient meets the criteria for use. If abnormal reactions such as vaginal bleeding or worsening itching occur during treatment, discontinue use immediately and seek medical attention.