Does taking dydrogesterone tablets affect blood HCG levels?

Nov 11, 2025 Source: Cainiu Health
Dr. Zhang Lu
Introduction
Under normal circumstances, dydrogesterone tablets do not directly affect the production of blood HCG levels. However, if embryonic development is abnormal, blood HCG levels may fail to rise normally even with the use of this medication. If embryonic development is normal, the drug may help maintain blood HCG levels within an appropriate range by supporting corpus luteum function. If there are any concerns, it is recommended to seek medical advice in advance. A detailed analysis is as follows:

Generally, dydrogesterone tablets do not directly affect the production of blood HCG levels. However, in cases of abnormal embryonic development, even with the use of this medication, blood HCG levels may fail to rise normally. If embryonic development is normal, the drug may help maintain blood HCG levels within an appropriate range by supporting corpus luteum function. If there are any concerns, it is recommended to consult a healthcare provider promptly. Detailed analysis is as follows:

Dydrogesterone works by supplementing progesterone to support endometrial stability, thereby facilitating embryo implantation and development. Its composition and mechanism of action differ from those of HCG (human chorionic gonadotropin), so it does not directly promote or inhibit HCG secretion. Therefore, it does not directly cause increases or decreases in blood HCG levels.

If the embryo itself has developmental issues such as chromosomal abnormalities leading to insufficient HCG secretion, blood HCG levels may remain low or rise slowly despite taking dydrogesterone, failing to reach expected levels for the gestational stage. Conversely, if embryonic development is normal but the mother has inadequate progesterone levels requiring dydrogesterone supplementation, the medication can improve the implantation environment and indirectly support normal HCG level progression, helping maintain a stable pregnancy.

While taking dydrogesterone, it is important to regularly monitor blood HCG and progesterone levels as directed by a physician. If HCG levels are abnormal, prompt consultation with a doctor is necessary to identify the underlying cause. Do not adjust the dosage or discontinue the medication without medical advice.