Why can Jiuyi Zhenxin Granules treat anxiety?

Nov 14, 2025 Source: Cainiu Health
Dr. Sun Lianqing
Introduction
Jiuyi Zhenxin Granules can treat anxiety, primarily due to the synergistic effects of multiple herbal ingredients in the formulation, which work by regulating internal organs and calming the mind. The specific mechanisms generally include nourishing the heart and calming the spirit to improve mood, invigorating qi and strengthening the spleen to consolidate the body's foundation, soothing the liver and relieving depression to alleviate emotional stagnation, providing sedative effects to ease nervous system states, and harmonizing qi and blood to balance bodily functions. A detailed analysis is as follows:

Jiuyi Zhenxin Granules can treat anxiety primarily because the multiple herbal ingredients in its formulation work synergistically to regulate internal organs and calm the mind. The effects generally include nourishing the heart and calming the spirit to improve mood, invigorating qi and strengthening the spleen to consolidate the body's foundation, soothing the liver and relieving depression to alleviate emotional stagnation, providing sedative effects to relax the nervous system, and harmonizing qi and blood to balance bodily functions. Specific mechanisms are as follows:

1. Nourishing the Heart and Calming the Spirit to Improve Mood: The formula contains herbal ingredients such as sour jujube seed (Ziziphi Spinosae Semen) and polygala root (Polygalae Radix), which nourish the heart and stabilize the mind. These components help relieve anxiety caused by restlessness of the spirit, reduce irritability and tension, gradually stabilize emotional states, and improve mood fluctuations associated with anxiety.

2. Invigorating Qi and Strengthening the Spleen to Consolidate the Foundation: Ingredients like codonopsis root (Codonopsis Radix) and poria (Poria) in the formula replenish qi and blood and strengthen the spleen and stomach. Enhanced spleen and stomach function improves nutrient digestion and absorption, providing sufficient energy for the body. When qi and blood are abundant, the mind is properly nourished, thereby reducing susceptibility to anxiety due to qi deficiency and physical weakness at the root cause.

3. Soothing the Liver and Relieving Depression to Alleviate Emotional Stagnation: The formula includes components that regulate liver qi, helping to unblock stagnant liver qi and relieve emotional suppression and anxiety caused by liver qi stagnation. By promoting smooth flow of qi, it reduces accompanying anxiety symptoms such as chest tightness and irritability resulting from emotional blockages.

4. Sedative Effects to Relax the Nervous System: Certain herbal components possess mild sedative properties that help soothe overexcited nerves, reduce neural tension, and alleviate symptoms such as mental restlessness and agitation commonly seen during anxiety. This assists the body and nervous system in achieving a more relaxed state.

5. Harmonizing Qi and Blood to Balance Bodily Functions: Through the synergistic action of various herbs, the formula helps regulate the circulation of qi and blood, maintaining balanced organ function. With smooth flow of qi and blood and coordinated organ activity, overall bodily stability is enhanced, reducing anxiety caused by functional imbalances and improving the overall anxiety condition.

Jiuyi Zhenxin Granules are a traditional Chinese medicine preparation and must be used under the guidance of a qualified physician. They should not be purchased or taken without medical supervision. During treatment, dosage and duration must strictly follow medical advice. If symptoms fail to improve or adverse reactions occur, medical attention should be sought promptly.