Can using Sophora flavescens gel during pregnancy affect the fetus?

Generally, when used as directed by a healthcare provider, matrine gel poses minimal risk to the fetus during pregnancy. However, self-medication or misuse may carry potential risks. Matrine gel is a topical traditional Chinese medicine that should be used appropriately according to individual pregnancy conditions. Detailed analysis is as follows:

Matrine gel is primarily used to treat gynecological inflammations. When applied locally, its active ingredients are mostly absorbed through the vaginal mucosa, with only a minimal amount entering the bloodstream. It usually does not cross the placenta and therefore rarely affects the fetus. Due to hormonal changes during pregnancy, women are more prone to vaginal infections. Doctors will determine whether treatment is necessary based on gestational age and severity of inflammation. Proper use of the medication can help control infection, thereby reducing indirect risks to the fetus caused by untreated inflammation.

If pregnant women self-medicate without confirming the underlying cause or use the product excessively over a prolonged period, the medication may trigger uterine contractions due to local irritation, increasing the risk of threatened miscarriage. Some pregnant women may be allergic to the components of the drug, and self-administration could lead to adverse reactions such as itching or swelling, potentially worsening their condition. Particularly during the first trimester—a critical period for fetal development—improper medication use may pose unknown risks.

Pregnant women experiencing gynecological discomfort should first seek medical evaluation and strictly follow medical advice when using any medication. Daily hygiene practices include keeping the external genital area clean, wearing cotton, breathable underwear, and changing and washing undergarments frequently. Avoid frequent douching with cleansing solutions, which may disrupt the natural balance of vaginal flora.