Does elevated rubella virus IgG in pregnant women affect the fetus?

Nov 14, 2025 Source: Cainiu Health
Dr. Zhang Lu
Introduction
In most cases, elevated rubella virus IgG levels in pregnant women have no impact on the fetus. Potential adverse effects on the fetus occur only when accompanied by positive IgM results or recent rubella virus infection. A comprehensive evaluation based on all test indicators is necessary to avoid unnecessary anxiety. If IgM is found to be positive or if there are symptoms suggestive of infection, prompt medical consultation and further testing are recommended.

Rubella virus IgG elevation in pregnant women usually has no adverse effect on the fetus. Only when it is accompanied by positive IgM or a recent rubella virus infection might there be potential risks to the fetus. A comprehensive evaluation based on all test results is necessary to avoid unnecessary anxiety. If IgM is found to be positive or if symptoms suggestive of infection occur, prompt medical consultation and further testing are recommended.

Elevated IgG antibodies against rubella virus typically indicate that the pregnant woman was previously infected with rubella or received the rubella vaccine, and has developed protective immunity. This immunity effectively prevents re-infection and does not affect fetal health via the placenta.

However, if both IgG levels are elevated and IgM antibodies are positive, this may indicate a recent rubella virus infection. In such cases, the virus could cross the placenta and infect the fetus, increasing the risk of congenital rubella syndrome and potentially causing fetal developmental abnormalities.

During pregnancy, it is important to complete routine prenatal viral screenings on schedule, avoid contact with individuals infected with rubella, maintain good indoor ventilation, practice personal hygiene, and strengthen overall health to reduce infection risks and provide a healthy environment for fetal development.