Does long-term use of ademetionine enteric-coated tablets (adenosine disodium sulfonate) affect menstruation?

Generally, whether long-term use of ademetionine disulfonate enteric-coated tablets affects menstruation needs to be evaluated based on individual circumstances. If discomfort occurs, it is recommended to seek medical advice promptly. The specific analysis is as follows:

If taken properly under a doctor's guidance, within the recommended dosage range, and if the individual has good tolerance to the medication, in most cases there will be no significant impact on menstruation. The drug primarily acts on liver metabolism and has not been clearly shown to directly interfere with the endocrine system; thus, menstrual cycle and flow can remain normal, and excessive concern is usually unnecessary.

However, long-term use at excessive doses or high sensitivity to the drug’s components may indirectly affect menstruation. Some individuals might experience menstrual irregularities, increased or decreased menstrual flow, which could be related to mild physiological stress responses induced by the medication. Changes in menstrual patterns should therefore be closely monitored.

It is essential to strictly follow medical instructions—do not adjust dosage or discontinue medication without consulting a doctor. Keep track of menstrual cycle and flow changes, and report any abnormalities to your physician promptly. Maintain regular sleep patterns during treatment, avoid staying up late and overexertion. Eat a balanced diet rich in nutrients and reduce intake of spicy or stimulating foods to support overall bodily stability.