How many times should intrauterine perfusion be performed for thin endometrium to be effective?

Nov 15, 2025 Source: Cainiu Health

Dr. Zhang Lu

Introduction

A typical effective treatment cycle for thin endometrium with intrauterine perfusion usually consists of 3–6 sessions. Most individuals will gradually experience improved endometrial thickness after completing the full course, meeting the requirements for conception. If there is no significant improvement in the endometrium after six perfusions, or if persistent abdominal pain, abnormal bleeding, or other issues occur, prompt medical consultation is recommended. Treatment is generally scheduled according to the menstrual cycle.

Endometrial thinning treatment with uterine cavity perfusion typically involves 3 to 6 sessions per effective treatment cycle. Most individuals experience a gradual increase in endometrial thickness after completing the full course as prescribed, meeting the requirements for conception. If there is no significant improvement in endometrial thickness after six perfusions, or if persistent abdominal pain, abnormal bleeding, or other symptoms occur, prompt medical consultation is recommended.

Treatment is generally scheduled according to the menstrual cycle, with 1–2 perfusions per cycle. Continuous treatment over 3–6 cycles allows medications to fully act on the endometrium, gradually repairing damage and promoting growth, while avoiding interruptions that could compromise treatment continuity.

The number of perfusions may be adjusted flexibly based on individual conditions. For thin endometrium caused by hormonal deficiency, improvement may be seen after 3–4 sessions; following surgery for intrauterine adhesions, more than six sessions may be required depending on recovery progress; if significant endometrial growth occurs after 2–3 sessions, subsequent perfusions may be appropriately reduced.

During treatment, maintain external genital hygiene, avoid sexual intercourse and tub baths, consume a diet rich in protein and estrogen-supporting foods, and maintain regular sleep patterns without staying up late, to create an optimal bodily environment for endometrial repair.

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