What does a positive hydrogen peroxide test at 36 weeks of pregnancy mean?

Nov 15, 2025 Source: Cainiu Health
Dr. Zhang Lu
Introduction
A positive hydrogen peroxide test at 36 weeks of pregnancy usually indicates abnormal hydrogen peroxide concentration in vaginal secretions, suggesting an imbalance in the vaginal flora. This may indicate bacterial vaginosis or simple dysbiosis, and management should be determined based on symptoms and examination results. Maintain external genital hygiene and dryness; wash the vulva daily with warm water, but avoid douching the vagina. Wear cotton, breathable underwear.

Positive hydrogen peroxide test at 36 weeks of pregnancy usually indicates an abnormal concentration of hydrogen peroxide in vaginal secretions, suggesting an imbalance in the vaginal microbiota. This may indicate bacterial vaginosis or simple dysbiosis, which should be differentiated and managed based on symptoms and examination results. Detailed analysis is as follows:

A positive hydrogen peroxide test at 36 weeks of gestation indicates an imbalance in the vaginal flora—specifically, a reduction in lactobacilli and overgrowth of other miscellaneous bacteria, leading to excessive production of hydrogen peroxide that exceeds the vagina's natural capacity for decomposition. During pregnancy, significantly elevated levels of estrogen and progesterone alter the vaginal pH environment, inhibiting lactobacilli growth and promoting proliferation of harmful bacteria. Additionally, relatively decreased immunity during pregnancy reduces resistance to pathogenic microorganisms in the vagina. Other contributing factors include poor external genital hygiene, wearing tight and non-breathable underwear, and overuse of vaginal washes, all of which can disrupt the balance of vaginal flora and result in a positive hydrogen peroxide test.

Maintain cleanliness and dryness of the external genital area by washing daily with warm water; avoid douching the vaginal canal. Wear cotton, breathable underwear and change it daily, preferably sun-drying for disinfection. Refrain from sexual intercourse to prevent cross-infection. Maintain a light diet, avoiding spicy and irritating foods, to enhance overall immunity. Follow medical advice for follow-up testing, and promptly inform your doctor if symptoms such as vulvar itching or abnormal vaginal discharge occur, to prevent inflammation from affecting maternal and fetal health.