Is suddenly becoming indifferent toward others a sign of mental illness?
Generally speaking, whether suddenly becoming distant toward others constitutes a mental illness depends on the specific context and accompanying symptoms. If there are abnormal behaviors, it is advisable to seek timely medical evaluation. The detailed analysis is as follows:

If sudden emotional detachment is accompanied by disorganized thinking or perceptual disturbances, it may be related to a psychiatric condition. For example, if someone who was previously warm and caring suddenly becomes indifferent toward family and friends, avoids communication, experiences hallucinations or delusions, loses interest in daily activities, and gradually becomes unable to manage basic self-care, such persistent detachment affecting social functioning should raise concern for psychotic symptoms, warranting prompt professional assessment.
Temporary emotional withdrawal triggered by a specific event typically does not indicate a mental illness. For instance, after experiencing setbacks or misunderstandings, a person may temporarily avoid social interactions; once emotions stabilize, normal social functioning resumes. This type of detachment is a natural stress response, has clear triggers, and resolves on its own, thus having no direct association with mental illness.
In daily interactions, offer companionship, initiate conversations in a gentle manner, and avoid pressuring the individual to communicate. Encourage participation in relaxing activities such as walking or gardening to help divert attention. Maintain a clean and structured living environment, provide appetizing meals, monitor emotional changes closely, and promptly accompany the person to seek professional help if detachment persists or abnormal behaviors emerge.