How to treat patients with moderate depression
Generally, treatment methods for patients with moderate depression mainly include medication therapy, psychotherapy, physical therapy, exercise therapy, and social support therapy. The details are as follows:

1. Medication Therapy
Medication is a key approach in treating moderate depression. Patients should take appropriate medications as prescribed by their doctors to improve symptoms. Commonly used medications include sertraline hydrochloride tablets, escitalopram oxalate tablets, mirtazapine tablets, venlafaxine hydrochloride sustained-release capsules, and duloxetine enteric-coated capsules. These drugs help alleviate symptoms such as low mood and lack of energy by regulating neurotransmitter levels in the brain.
2. Psychotherapy
Psychotherapy helps patients adjust their cognitive patterns and improve negative emotional responses. Common approaches include cognitive behavioral therapy (CBT) and supportive psychotherapy. CBT guides patients to identify and correct negative thinking patterns and develop more positive cognitions. Supportive psychotherapy provides emotional support through active listening and encouragement, enhancing patients’ confidence in treatment.
3. Physical Therapy
Physical therapy can serve as an adjunctive method to relieve symptoms of moderate depression. Common techniques include repetitive transcranial magnetic stimulation (rTMS) and electroconvulsive therapy (ECT). rTMS uses magnetic fields to stimulate specific areas of the brain, thereby modulating neural function. ECT is typically reserved for patients with more severe symptoms or poor response to medication, and it can rapidly improve depressive states.
4. Exercise Therapy
Exercise therapy promotes physical and mental recovery through regular physical activity. Patients may choose activities such as jogging, swimming, or yoga. During exercise, the brain releases neurotransmitters such as endorphins, which help reduce anxiety and depressive feelings. Additionally, exercise improves physical fitness, sleep quality, and appetite, thereby enhancing overall well-being.
5. Social Support Therapy
Social support therapy leverages the support of family, friends, and community groups to aid patient recovery. Family members should spend time communicating with the patient and offer understanding and patience. Friends and relatives can encourage participation in social activities to prevent isolation. Communities can provide rehabilitation resources, helping patients feel cared for and reducing psychological stress.
In addition, during treatment, patients must strictly follow medical instructions regarding medication use and should not alter dosages or discontinue medication without consultation. Regular follow-up visits to the hospital are essential. If adverse drug reactions or symptom fluctuations occur, patients should promptly communicate with their doctors to adjust the treatment plan and promote stable recovery.