How long does it take for dilated pupils to recover after taking escitalopram oxalate tablets?
Nov 21, 2025
Source: Cainiu Health
Dr. Zhang Baohua
Introduction
As an antidepressant, escitalopram oxalate tablets may cause pupil dilation by blocking the acetylcholine effects of the parasympathetic nervous system. Its elimination half-life is approximately 30 hours, and it takes about 4 to 6 half-lives for the drug to be gradually metabolized and cleared. During this period, the symptom of pupil dilation usually diminishes. However, individual differences in metabolic capacity may affect the recovery rate, and some patients might experience relief within a shorter timeframe.
Under normal circumstances, pupil dilation may occur after taking escitalopram oxalate tablets and may resolve within 5 to 8 days or even several hours after discontinuation, with specific recovery time varying from person to person. If any abnormalities occur, prompt medical consultation is recommended. Detailed analysis is as follows:
As an antidepressant, escitalopram oxalate tablets may cause pupil dilation by blocking acetylcholine activity in the parasympathetic nervous system. The elimination half-life of this drug is approximately 30 hours, and it generally takes 4–6 half-lives (i.e., 5–8 days) for the drug to be gradually metabolized and cleared from the body, during which time pupil dilation symptoms typically subside. However, individual differences in metabolic capacity may affect the recovery rate, and some patients may experience symptom relief in a shorter period.
If pupil dilation is accompanied by severe headache, blurred vision, or mood fluctuations, excessive dosage or worsening adverse reactions should be suspected. In such cases, recovery may take longer and medical intervention may be required to adjust the treatment regimen. If symptoms persist beyond one week without improvement or if other abnormal manifestations appear, immediate medical evaluation is necessary to rule out potential risks.
During treatment, it is advisable to avoid direct exposure to bright light, minimize prolonged close-up visual tasks, and maintain regular sleep patterns. If symptoms persist or worsen, promptly consult a physician to determine whether dose adjustment or medication switch is needed.
