Is it acceptable to take only oxcarbazepine during the stable phase of bipolar disorder?

Generally, whether oxcarbazepine alone can be used during the stable phase of bipolar disorder depends on an individual assessment of the condition. Some patients may maintain stability with monotherapy, while more complex cases may require combination treatment. If any abnormalities occur, prompt medical consultation is recommended. Detailed analysis is as follows:

As an antiepileptic drug, oxcarbazepine is primarily used in the treatment of bipolar disorder to control manic episodes by stabilizing neuronal membranes and reducing abnormal electrical discharges. For patients in a stable phase with mild manic symptoms, no depressive or mixed episodes, and who have previously tolerated oxcarbazepine well, physicians may recommend maintenance therapy with oxcarbazepine alone, along with regular monitoring of blood drug levels and emotional status.

If a patient exhibits rapid cycling, mixed episodes, or a tendency toward depressive episodes, or if previous monotherapy has been ineffective, combination therapy with mood stabilizers such as lithium or valproate, or second-generation antipsychotics, may be necessary. Additionally, patients with impaired liver or kidney function, abnormal drug metabolism, or comorbid medical conditions are at higher risk when using monotherapy and require individualized treatment adjustments.

During treatment, it is essential to strictly follow medical instructions, attend regular follow-up appointments to evaluate efficacy and adverse effects, and avoid adjusting dosages or discontinuing medication without guidance. Immediate medical attention should be sought if mood fluctuations, increased frequency of seizures, or severe allergic reactions occur.