Which is more effective for treating acute anxiety: Xuefu Zhuyu Capsules or Shugan Jieyu Capsules?

Nov 21, 2025 Source: Cainiu Health
Dr. Sun Lianqing
Introduction
Xuefu Zhuyu Capsules belong to a class of traditional Chinese medicine known for promoting blood circulation and removing blood stasis. The main ingredients, such as Angelica sinensis and Ligusticum chuanxiong, exert their effects by improving microcirculation, and are indicated for pain or symptoms related to cerebral ischemia caused by blood stasis. The pharmacological mechanism has no direct connection with the neurochemical imbalances underlying anxiety disorders, and thus the capsules alone are unlikely to improve core symptoms of anxiety. Any reported feelings of comfort from some patients may stem from a placebo effect.

Generally, Xuefu Zhuyu Capsules have limited effect on acute anxiety disorder, and Shugan Jieyu Capsules may help alleviate symptoms but cannot provide a cure. If any abnormalities occur, prompt medical consultation is recommended. Detailed analysis is as follows:

Xuefu Zhuyu Capsules are a traditional Chinese medicine classified as promoting blood circulation and removing blood stasis. Their main ingredients, such as Angelica sinensis and Chuanxiong, exert effects by improving microcirculation, making them suitable for pain or symptoms related to cerebral hypoperfusion caused by blood stasis. However, their pharmacological mechanism is not directly related to the neurotransmitter dysregulation underlying anxiety disorders, so they are unlikely to significantly improve core anxiety symptoms when used alone. Any reported sense of comfort among some patients may stem from placebo effects.

Shugan Jieyu Capsules contain ingredients such as Hypericum perforatum and Acanthopanax senticosus, which can help regulate the balance of central nervous system neurotransmitters. They are effective in improving symptoms associated with mild to moderate anxiety, such as low mood, difficulty falling asleep, and feelings of tension or restlessness. However, this medication should be used in conjunction with psychotherapy and conventional anti-anxiety drugs. Long-term use may lead to dependence, and caution is advised in patients with impaired liver function.

Medication must be taken strictly according to medical instructions during treatment. Self-adjusting dosage or combining with other drugs should be avoided. If symptoms worsen, liver function abnormalities occur, or severe mood fluctuations develop, discontinue the medication immediately and seek professional evaluation at a hospital.

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