What is the concentration of sodium chloride injection?

Sodium chloride injection is commonly available in a 0.9% concentration, with a hypertonic 10% formulation also available. The 0.9% solution is isotonic and the most widely used in clinical practice, while the 10% concentration is reserved for specific medical conditions. If discomfort such as redness and swelling at the infusion site, dizziness, nausea, or other adverse reactions occur during use, prompt medical attention is recommended.

The osmotic pressure of 0.9% sodium chloride injection is close to that of human blood and tissue fluid, making it known as normal saline. It is used to replenish fluids and electrolytes and maintain the body's osmotic balance. It is commonly administered for dehydration or fluid replacement after blood loss, and can also serve as a diluent for medications.

10% sodium chloride injection is a hypertonic solution with an osmotic pressure significantly higher than that of human body fluids. It is primarily used to treat severe hyponatremia and hypochloremia, rapidly increasing serum sodium and chloride levels. However, the infusion rate and dosage must be strictly controlled to avoid risks such as cellular dehydration.

Sodium chloride injection should be used strictly according to medical instructions, with appropriate concentration selected based on the patient's condition. During infusion, the rate should be carefully regulated, especially to avoid rapid administration of hypertonic solutions. The product should be stored sealed in a cool, dry place, protected from direct sunlight and contamination.