What is the normal value of CO2CP?

Nov 25, 2025 Source: Cainiu Health
Dr. Wang Lei
Introduction
CO2CP generally refers to carbon dioxide combining power. The normal value for carbon dioxide combining power is 22–29 mmol/L. This index reflects the body's acid-base balance status and bicarbonate reserve, serving as an important reference for assessing metabolic acid-base disturbances. If test results fall outside this range, or if symptoms such as fatigue or abnormal breathing occur, prompt medical attention is recommended.

CO2CP generally refers to carbon dioxide combining power. The normal range for carbon dioxide combining power is 22–29 mmol/L. This index reflects the body's acid-base balance and bicarbonate reserve status, serving as an important reference for assessing metabolic acid-base disturbances. If test results fall outside this range, or if symptoms such as fatigue or abnormal breathing occur, prompt medical consultation is recommended.

Carbon dioxide combining power primarily reflects the concentration of bicarbonate ions in plasma, which are a key substance in regulating the body's acid-base balance. Values within the normal range indicate stable acid-base metabolism, with effective buffering of acidic or alkaline substances and maintenance of internal environmental homeostasis.

Values below 22 mmol/L may suggest metabolic acidosis, commonly seen in conditions such as diarrhea or renal insufficiency; values above 29 mmol/L may indicate metabolic alkalosis, often associated with vomiting or hypokalemia. Further diagnostic tests are needed to determine the underlying cause.

To support health, maintain regular sleep patterns and avoid staying up late, eat a balanced diet rich in vegetables, fruits, and high-quality protein, and avoid long-term excessive consumption of highly acidic or alkaline foods. Engage in moderate exercise to enhance metabolic function and maintain stable respiratory and circulatory systems, thereby supporting proper acid-base regulation.