Can I use cooking wine in dishes while taking duloxetine hydrochloride enteric-coated capsules?

Generally, it is not recommended to use cooking wine when taking this medication. If absolutely necessary, a minimal amount may be considered, provided that the alcohol is completely evaporated through thorough cooking. If in doubt, it is advisable to consult a healthcare professional beforehand. Detailed analysis is as follows:

If cooking wine is used in normal quantities during cooking, even after heating, trace amounts of alcohol may still remain. Consuming alcohol together with duloxetine hydrochloride enteric-coated capsules may enhance the drug's effects on the central nervous system, potentially causing dizziness, drowsiness, or other discomforts. It may also increase the liver’s metabolic burden, affect the drug’s efficacy, and raise the risk of adverse reactions, which could hinder recovery.

If seasoning necessitates the use of cooking wine, only a very small amount (e.g., just a few drops for flavor) should be used, and prolonged high-temperature cooking must ensure complete evaporation of alcohol. This approach may reduce risks—especially for individuals without liver disease or a history of alcohol sensitivity. However, uncertainty remains, and potential effects cannot be entirely ruled out; therefore, caution is strongly advised.

During treatment with this medication, a light and simple diet is recommended. Avoid alcohol-containing seasonings whenever possible. Inform your doctor about your dietary habits during regular follow-up visits. If any discomfort occurs after consuming dishes containing cooking wine, seek medical attention promptly to ensure safe medication use.