What are the contraindications of tetracaine hydrochloride gel?

Under normal circumstances, tetracaine hydrochloride gel is used as a local anesthetic, and its contraindications mainly include: those allergic to the components should not use it; it should not be applied to damaged mucous membranes; patients with severe cardiovascular or cerebrovascular diseases should avoid it; it is prohibited for children; and there are specific drug interaction restrictions. The details are as follows:

1. Contraindicated in individuals allergic to components: Patients who are allergic to tetracaine or other ester-type local anesthetics may develop rashes, urticaria after administration, and in severe cases, anaphylactic shock. Therefore, its use is strictly prohibited, and any history of allergy must be clearly reported before medication.

2. Contraindicated on damaged mucous membranes: The drug needs to be absorbed through mucous membranes to take effect. When ulcers, erosion, or damage exist on the mucosa, the absorption rate of the drug increases significantly, which can easily lead to a sudden rise in blood drug concentration, causing toxic reactions such as dizziness and tinnitus, and even endanger life.

3. Contraindicated in patients with severe cardiovascular or cerebrovascular diseases: The drug may inhibit the cardiac conduction system, reduce myocardial contractility, and may also cause blood pressure fluctuations. In patients with severe coronary heart disease, hypertensive crisis, or arrhythmia, its use may worsen the condition and trigger angina pectoris or heart failure.

4. Contraindicated in children: Children have delicate skin and mucous membranes, resulting in higher drug absorption rates than adults. Additionally, their liver and kidney functions are not fully developed, leading to weaker drug metabolism capacity. This makes them highly susceptible to toxic reactions after using the drug; therefore, this medication is explicitly prohibited for pediatric use.

5. Drug interaction contraindications: It should not be used concurrently with sulfonamide drugs, as this may trigger allergic reactions. Concurrent use with other local anesthetics should also be avoided, as this could enhance both anesthetic effects and toxicity, increasing the risk of respiratory depression and neurological damage.

Tetracaine hydrochloride gel is a prescription medication that must be administered by trained healthcare professionals. Self-purchase and application are strictly prohibited. Close monitoring of bodily responses is required during use, and dosage and application area must be strictly controlled to ensure safe medication use.