What are the clinical applications of glucose?

Nov 25, 2025 Source: Cainiu Health
Dr. Huang Yuhong
Introduction
The clinical applications of glucose mainly include energy supplementation, correction of hypoglycemia, providing a fluid carrier, supporting nutritional therapy, and assisting in drug dilution. It is a commonly used fundamental medication in clinical practice and should be used appropriately according to the patient's condition. If hyperglycemia, diabetic ketoacidosis, or similar conditions occur, prompt medical attention is recommended. Suitable for patients with inadequate food intake or excessive consumption.

Glucose is commonly used in clinical practice for energy supplementation, correction of hypoglycemia, serving as a fluid vehicle, supporting nutritional therapy, and assisting in drug dilution. It is a fundamental medication widely used in clinical settings and must be administered according to the patient's specific condition. If conditions such as hyperglycemia or diabetic ketoacidosis occur, prompt medical attention is recommended.

1. Energy supplementation: Indicated for patients with inadequate food intake or excessive consumption, such as those experiencing severe vomiting, diarrhea, high fever, or postoperative fasting. Glucose rapidly provides energy to the body, alleviating symptoms of energy deficiency like fatigue and dizziness.

2. Correction of hypoglycemia: Used for patients experiencing hypoglycemic episodes. Administered intravenously or orally, it quickly raises blood glucose levels and relieves symptoms such as palpitations, sweating, and confusion. It is a key drug in the emergency management of hypoglycemia.

3. Fluid vehicle: Frequently used as a base component in intravenous fluid therapy. Combined with electrolytes, vitamins, and other medications, it helps rehydrate patients and maintain the body’s water, electrolyte, and acid-base balance.

4. Support of nutritional therapy: For patients unable to eat normally—such as those with gastrointestinal disorders or critical illness—glucose in enteral or parenteral nutrition formulations ensures basic nutritional supply and supports metabolic function.

5. Drug dilution: Serves as a diluent for various injectable drugs, including antibiotics and hormones. It reduces vascular irritation caused by medications, promotes steady drug absorption, and ensures safe and effective administration.

Glucose administration requires strict control of dosage and infusion rate. Diabetic patients should monitor blood glucose levels and adjust dosage accordingly. Store in a sealed container in a cool place, away from direct sunlight and high temperatures. Monitor patient response during infusion to ensure proper and safe use.