What blood types are compatible for transfusion with type O blood?

O-type blood can be given in small amounts to recipients with A, B, AB, or O blood types when serving as a donor. However, when an O-type individual is the recipient, they can only receive O-type blood. Blood transfusions must strictly follow blood type compatibility principles to avoid hemolytic reactions. If symptoms such as fever, chills, or difficulty breathing occur during transfusion, inform medical staff immediately and seek medical attention.

Red blood cells of O-type blood lack A and B antigens, so they do not trigger agglutination reactions with antibodies in recipients of other blood types. For this reason, O-type blood is known as the "universal donor," although it should only be administered in small quantities, as large volumes may still provoke immune reactions.

When receiving blood, individuals with O-type blood have anti-A and anti-B antibodies in their serum. If they receive blood from another blood type, these antibodies will bind to A or B antigens on the donor's red blood cells, causing red blood cell agglutination and rupture, leading to severe hemolytic reactions that may be life-threatening.

Prior to transfusion, rigorous blood typing and cross-matching tests must be performed to ensure blood compatibility. During transfusion, the infusion rate should be carefully controlled to prevent excessive strain on the body. After transfusion, adequate rest, hydration, and nutritional support are recommended to help the body recover and adapt.