What are the precautions for using sodium valproate tablets?

Generally, sodium valproate tablets, as a commonly used antiepileptic drug, require attention to several key points during use, including taking the medication as prescribed, regular monitoring of health indicators, awareness of potential drug interactions, strict management for special populations, and lifestyle adjustments to support treatment. The details are as follows:

1. Take medication as prescribed by your doctor: It is essential to strictly follow the dosage and frequency prescribed by your physician. Do not adjust the dose or stop the medication abruptly without medical advice. Sudden discontinuation may increase the frequency of seizures. Any changes to the treatment plan should be discussed with your doctor in advance and carried out gradually under professional guidance.

2. Regular monitoring of health indicators: Liver function, complete blood count, and other relevant parameters should be regularly checked during treatment, especially during the initial phase of therapy and when dosage adjustments are made. Some individuals may experience elevated transaminase levels or reduced platelet counts; early detection allows timely intervention and helps prevent worsening complications.

3. Be cautious of drug interactions: If other medications—including traditional Chinese medicines or dietary supplements—are needed during treatment, inform your doctor beforehand. Sodium valproate may interact with anticoagulants, antidepressants, and other drugs, potentially affecting efficacy or increasing the risk of side effects such as nausea and dizziness.

4. Strict control for special populations: Pregnant and breastfeeding women should use this medication cautiously, as it may have adverse effects on the fetus or infant. Use should only occur after a thorough risk-benefit assessment by a physician. The drug is contraindicated in patients with severe liver dysfunction. Dosage for children and elderly patients should be adjusted based on body weight or overall health status, with close observation of treatment response.

5. Support treatment through lifestyle modifications: Alcohol consumption should be avoided during treatment, as alcohol can enhance the central nervous system depressant effects of the drug, leading to increased drowsiness and slowed reaction times. Maintain a regular sleep schedule, avoid excessive fatigue and intense emotional fluctuations, and eat a balanced diet to create an optimal physiological environment for the medication to work effectively.

Sodium valproate tablets are prescription-only medication, and safe usage is crucial. Patients should proactively communicate any experiences or concerns during treatment to their doctors and integrate these precautions into daily life to fully support therapeutic outcomes.