What are the precautions for using Diltiazem Hydrochloride Tablets?
Nov 25, 2025
Source: Cainiu Health
Dr. Tian Hongbo
Introduction
Precautions for taking Diltiazem Hydrochloride Tablets generally include adjusting the dosage as directed by a physician, monitoring blood pressure and heart rate, paying attention to drug interactions, and watching for adverse reactions. The medication should be taken strictly according to the prescribed dose; patients must not adjust the dosage on their own or stop the medication abruptly, as sudden discontinuation may lead to rebound of original symptoms, such as worsening angina. Any dosage adjustment should be conducted gradually under medical evaluation.
Precautions for taking Diltiazem Hydrochloride Tablets generally include following medical advice to adjust dosage, monitoring blood pressure and heart rate, paying attention to drug interactions, identifying contraindicated populations, and being alert to adverse reactions. Specific details are as follows:
1. Adjust dosage under medical guidance: The medication must be taken strictly according to the prescribed dose. Do not alter the dosage or abruptly discontinue use without medical advice, as sudden discontinuation may lead to rebound of original symptoms, such as worsening angina. Any dosage adjustment should be made gradually after evaluation by a physician.
2. Monitor blood pressure and heart rate: Regular monitoring of blood pressure and heart rate is necessary during treatment. This drug may cause hypotension (low blood pressure) and bradycardia (slow heart rate). If excessively low blood pressure (e.g., dizziness, fatigue) or slow heart rate (e.g., chest tightness, shortness of breath) occurs, promptly inform your doctor, who will determine whether medication adjustments are needed.
3. Be aware of drug interactions: Inform your doctor if you are concurrently taking other medications, such as antihypertensives, antidiabetic drugs, or antifungal agents, to avoid potential drug interactions that could affect efficacy or increase the risk of adverse effects, ensuring safe and effective treatment.
4. Identify contraindicated populations: The drug is contraindicated in patients with severe hypotension, second- to third-degree atrioventricular block, or sick sinus syndrome. Patients with impaired liver or kidney function should use the drug with caution under medical supervision to prevent increased organ burden or serious complications.
5. Watch for adverse reactions: Possible side effects after taking the drug include headache, facial flushing, and lower limb edema. Mild symptoms may be observed without immediate intervention; however, if severe reactions such as rash, difficulty breathing, or palpitations occur, discontinue the drug immediately and seek medical attention for appropriate management.
Take the medication at consistent times daily to maintain stable blood concentration. Attend regular follow-up visits, as doctors will adjust the treatment plan based on disease progression. Long-term, unmonitored use of the drug should be avoided.
