What Are the Available Antipyretics?

Jul 25, 2021 Source: Cainiu Health
Dr. Zhang Jian
Introduction
Antipyretic drugs primarily include nonsteroidal anti-inflammatory drugs (NSAIDs) with antipyretic and analgesic properties, such as ibuprofen, aspirin, acetaminophen (paracetamol), indomethacin, nimesulide, and celecoxib. These agents are commonly used for fever reduction. Additionally, certain intramuscular injections—such as Xiao Chai Hu injection and compound aminopyrine–phenobarbital injection—may also be employed for antipyretic therapy.

Antipyretic medications primarily include the following:

First, nonsteroidal anti-inflammatory drugs (NSAIDs) with antipyretic and analgesic properties—mainly used for fever reduction. Examples include ibuprofen, aspirin, acetaminophen (paracetamol), indomethacin, nimesulide, and celecoxib.

These medications are highly effective for fever reduction; typically, one to two tablets are administered per dose. If the desired antipyretic effect is not achieved, a repeat dose may be given after an interval of 6–8 hours.Second, parenteral (intramuscular) antipyretic agents may be used, such as Xiao Chai Hu Injection (Minor Bupleurum Injection) or Compound Aminopyrine and Barbital Injection.Third, certain traditional Chinese patent medicines may also be employed for fever management, including Xiao Chai Hu Granules (Minor Bupleurum Granules) and Isatis Root (Ban Lan Gen) preparations.