What is otolith disease?

Nov 26, 2025 Source: Cainiu Health
Dr. Lu Cheng
Introduction
In general, benign paroxysmal positional vertigo (BPPV) is a dizziness disorder caused by the dislodging of otoliths in the inner ear. It commonly occurs in middle-aged and elderly individuals, with sudden onset but a favorable treatment outcome. The otoliths in the inner ear are calcium carbonate crystals responsible for sensing gravity and linear acceleration, normally attached to the otolithic membrane. Otoliths may become dislodged due to factors such as head trauma, inner ear ischemia, aging, or inner ear diseases.

  In general, otolith disease (benign paroxysmal positional vertigo, BPPV) is a type of dizziness caused by the dislodging of otoliths in the inner ear. It commonly occurs in middle-aged and elderly individuals, with sudden onset but generally good treatment outcomes. A detailed analysis is as follows:

  Otoliths in the inner ear are calcium carbonate crystals responsible for sensing gravity and linear acceleration, normally attached to the otolithic membrane. When head trauma, inner ear ischemia, aging, or inner ear diseases cause these otoliths to become dislodged, they move with the lymphatic fluid and stimulate hair cells, leading to vestibular dysfunction. The hallmark symptom of this condition is positional vertigo—patients experience a sudden sensation of spinning when changing head positions, such as turning over in bed, sitting up, or bending the head forward. Episodes typically last from several seconds to tens of seconds and may be accompanied by nausea and nystagmus, but without tinnitus or hearing loss.

  Diagnosis of otolith disease primarily relies on positional testing, during which doctors observe nystagmus by performing specific head maneuvers to confirm the diagnosis. Treatment mainly involves otolith repositioning procedures, using specialized manual techniques or instruments to guide the displaced otoliths back to their proper position. Most patients experience symptom relief after 1–2 repositioning sessions.

  In daily life, it is important to avoid sudden, vigorous head movements and rapid standing. Adopting appropriate sleeping positions can also help reduce the risk of otoliths becoming dislodged again.

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