Will taking too much Donglingcao syrup lead to drug resistance?

Nov 26, 2025 Source: Cainiu Health
Dr. Sun Lianqing
Introduction
Failure to follow medical instructions, long-term excessive use of medication, or continued use without symptoms may result in prolonged exposure of potential pathogens in the body to the drug components. This can promote gradual adaptation of the pathogens to the drug environment, leading to genetic mutations or metabolic changes, thereby reducing the drug's inhibitory effect on the pathogens and increasing the likelihood of drug resistance in subsequent treatments. It may also加重 the metabolic burden on the liver and kidneys.

Under normal circumstances, short-term use of Donglingcao Syrup at the recommended dosage is unlikely to lead to drug resistance. However, long-term excessive use or abuse may increase the risk of developing resistance. If in doubt, it is advisable to consult a healthcare professional in advance. Specific analysis is as follows:

If used for short-term symptoms such as pharyngitis, following the prescribed dosage and treatment duration as indicated on the product label or by a physician, and discontinuing the medication promptly after symptom relief, the drug's action within the body remains brief. This makes it difficult for pathogens to adapt, and therefore, drug resistance typically does not develop. The syrup can effectively exert its intended effects of clearing heat and relieving sore throat.

However, if used without following medical advice—such as taking excessive doses over a prolonged period or continuing medication despite absence of symptoms—the active components may continuously affect any existing pathogens in the body. This sustained exposure may encourage pathogens to gradually adapt to the drug environment, leading to genetic mutations or metabolic changes that reduce the drug’s inhibitory effect on the pathogens. Consequently, this increases the likelihood of drug resistance with future treatments and may also place additional metabolic strain on the liver and kidneys.

Donglingcao Syrup should be taken strictly according to the recommended dosage and duration. Do not increase the dose or extend the treatment period without guidance. If symptoms do not improve after three days of use, discontinue the medication and seek medical advice to adjust the treatment plan, so as to avoid drug resistance or other health issues caused by improper use.

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