Why does a pregnant woman experience itching on the inner thigh at night?

Nov 28, 2025 Source: Cainiu Health
Dr. Liu Wenmin
Introduction
In general, pregnant women may experience itching on the inner thighs at night due to hormonal changes, friction, intrahepatic cholestasis of pregnancy, eczema, fungal infections, or other causes. If discomfort occurs, it is recommended to seek timely medical evaluation and treatment at a正规 hospital. In daily life, maintain clean and dry skin, avoid frequent washing with hot water, follow a light diet, and reduce intake of spicy or irritating foods.

Generally, if a pregnant woman experiences itching on the inner thighs at night, it may be caused by hormonal changes, friction irritation, intrahepatic cholestasis of pregnancy, eczema, or fungal infection. If discomfort occurs, it is recommended to seek timely medical evaluation and treatment at a正规 hospital. Specific analyses are as follows:

1. Hormonal Changes

Elevated estrogen levels during pregnancy increase sebaceous gland secretion, causing the inner thighs to become moist and sweaty. Accumulated sweat at night can irritate the skin and cause itching. Clean the inner thighs daily with lukewarm water, dry thoroughly, then apply a gentle moisturizer specifically formulated for pregnant women. Choose cotton undergarments and sleepwear that are breathable.

2. Friction Irritation

Weight gain during pregnancy increases skin-to-skin friction on the inner thighs, or wearing tight synthetic clothing may exacerbate irritation, especially at night when physical activity decreases, leading to intensified itching. Switch to loose-fitting cotton clothing, avoid overly tight pants, and consider applying soft, breathable protective pads to the inner thighs to reduce friction.

3. Intrahepatic Cholestasis of Pregnancy (ICP)

Abnormal bile acid metabolism during pregnancy leads to bile acid accumulation, which stimulates skin nerves and causes itching—particularly on the inner thighs and throughout the body—with symptoms often worsening at night. Follow your doctor’s instructions to take ursodeoxycholic acid capsules, ademetionine 1,4-butanedisulfonate enteric-coated tablets, and vitamin C tablets. Regular monitoring of liver function and serum bile acid levels is essential.

4. Eczema

Pregnancy-related weakening of the skin barrier combined with a humid environment may trigger eczema on the inner thighs, presenting as redness, papules, and itching, with symptoms often aggravated by increased body temperature at night. Under medical guidance, treatments such as calamine lotion, hydrocortisone butyrate cream, or loratadine tablets may be used. Keep the affected area clean and dry.

5. Fungal Infection

The warm, moist environment of the inner thighs provides ideal conditions for fungal growth, leading to tinea corporis (ringworm), characterized by ring-shaped red rashes and itching, which typically worsens at night. Use antifungal medications such as clotrimazole cream, miconazole nitrate cream, or terbinafine tablets as directed by a physician. Avoid sharing towels with family members and wash and dry clothes separately.

In daily life, maintain clean and dry skin, and avoid frequent washing with hot water. Eat a light diet and minimize intake of spicy or irritating foods. Maintain regular sleep patterns and avoid staying up late. Use mild, non-irritating skincare products, refrain from scratching when itching occurs, and seek prompt medical attention to determine the underlying cause.