What should a pregnant woman do if she develops plantar warts on the soles of her feet?

Nov 28, 2025 Source: Cainiu Health
Dr. Liu Wenmin
Introduction
Plantar warts on the soles of pregnant women may be caused by decreased immunity, foot pressure and friction, HPV infection, secondary infection of warts, or impaired skin barrier. It is recommended to seek medical attention promptly, identify the underlying cause, and under a doctor's guidance, improve the condition through safe general treatments, medications, or other appropriate methods. Maintain good foot hygiene in daily life, dry feet thoroughly after washing—especially between the toes.

In general, the development of plantar warts on the feet of pregnant women may be caused by factors such as decreased immunity, foot pressure and friction, HPV infection, secondary infection of warts, or impaired skin barrier. It is recommended to seek medical attention promptly, identify the underlying cause, and then improve the condition through safe general treatments, medications, and other methods under a doctor's guidance. The specific analysis is as follows:

1. Decreased Immunity: During pregnancy, the maternal immune system undergoes adjustments and resistance decreases, making it easier for viral infections like plantar warts to occur. Ensure adequate sleep—8 to 10 hours per day—and increase intake of high-quality proteins such as eggs and milk to strengthen the body's immunity.

2. Foot Pressure and Friction: Weight gain during pregnancy increases pressure on the feet, leading to skin damage from friction, which creates opportunities for viral invasion. Choose loose, breathable flat shoes with soft soles, avoid prolonged standing or walking, and soak feet in warm water daily to relieve foot pressure.

3. HPV Infection: Human papillomavirus (HPV) invades the skin of the feet, causing abnormal proliferation of keratinocytes and forming rough-surfaced, painful plantar warts. During pregnancy, physical treatments are preferred; cryotherapy can be performed under a doctor’s supervision. Medications such as recombinant human interferon α2b gel, imiquimod cream, or compound polymyxin B ointment may be used according to medical advice to reduce viral activity.

4. Secondary Infection of Warts: Bacteria may invade when plantar warts become damaged, resulting in redness, swelling, and exudation, worsening pain. Under medical guidance, safe topical antibiotics such as mupirocin ointment, fusidic acid cream, or erythromycin ointment should be used, avoiding oral medications that could affect the fetus.

5. Impaired Skin Barrier: Dryness and cracking of the feet compromise the integrity of the skin barrier, making it easier for viruses to enter. After soaking feet daily, apply a gentle moisturizer specifically designed for pregnant women to keep the skin hydrated. Avoid peeling off the keratin layer on the surface of warts manually to prevent further damage to the skin barrier.

Maintain good foot hygiene—dry feet thoroughly after washing, especially between the toes. Avoid sharing slippers or foot basins with family members to prevent virus transmission. Inform your doctor about the presence of plantar warts during routine prenatal checkups, and adjust treatment plans according to gestational age to ensure the safety of both mother and baby.