What causes white, flaky dead skin at the corners of the mouth upon waking, and what should be done about it?

Generally, white dry skin at the corners of the mouth upon waking in the morning may be caused by factors such as dry environment, insufficient water intake, angular cheilitis, cheilitis, or vitamin B complex deficiency. If discomfort occurs, it is recommended to seek timely medical evaluation and treatment at a正规 hospital. Specific causes are analyzed as follows:

1. Dry Environment

Dry indoor air during nighttime sleep can cause excessive moisture loss from the skin at the corners of the mouth, leading to dryness and shedding of the stratum corneum. Using a humidifier in the room before bedtime, applying non-irritating lip balm to the corners of the mouth, and avoiding mouth breathing during sleep can help prevent this condition.

2. Insufficient Water Intake

Inadequate fluid intake during the day, combined with ongoing metabolic water consumption at night, leaves the skin at the corners of the mouth dehydrated, resulting in keratin buildup and peeling. It is recommended to drink 1500–2000 mL of water daily. A small amount of water before bedtime (one hour prior) is acceptable, but excessive intake should be avoided to prevent disrupted sleep.

3. Angular Cheilitis

Bacterial or fungal infection of the mouth corners can trigger an inflammatory response, causing redness, swelling, and flaking of the skin. Treatment may include erythromycin ointment, clotrimazole cream, or oral vitamin B2 tablets as directed by a physician. Clean the corners of the mouth promptly after eating to prevent irritation from food residue.

4. Cheilitis

Cheilitis caused by allergens or irritants leads to dry, flaky skin at the corners of the lips and mouth, often accompanied by itching or burning pain. Under medical guidance, medications such as loratadine tablets or levocetirizine hydrochloride tablets may be taken orally, and topical tacrolimus ointment may be applied. Avoid contact with potential allergens such as lipstick and toothpaste.

5. Vitamin B Complex Deficiency

Deficiency in vitamins such as B2 and B6 impairs mucosal and skin repair, leading to rough, flaky skin at the corners of the mouth. Oral supplements including vitamin B2 tablets, vitamin B6 tablets, and compound vitamin B tablets may be taken under medical supervision. Increase dietary intake of eggs, lean meat, and fresh fruits and vegetables.

In daily life, maintain appropriate indoor humidity; develop consistent hydration habits; avoid picking or tearing dry skin at the corners of the mouth to prevent infection; eat a balanced diet to ensure adequate vitamin intake; and use gentle skincare products to minimize skin irritation.