Is compound ketoconazole cream a prescription drug?

Nov 29, 2025 Source: Cainiu Health
Dr. Liu Wenmin
Introduction
In general, compound ketoconazole ointment is a prescription medication. Before application, clean the affected skin area and ensure it is dry before applying the ointment, avoiding excessive contact with healthy skin. Strictly follow medical instructions regarding dosage and duration of use; do not increase the dose or prolong treatment without authorization. Monitor skin reactions carefully during treatment.

Generally, compound ketoconazole ointment is a prescription medication. The detailed analysis is as follows:

Compound ketoconazole ointment contains two main ingredients: ketoconazole and clobetasol propionate. The former is an antifungal agent, while the latter belongs to the corticosteroid (glucocorticoid) class. Prolonged or inappropriate use of glucocorticoids may lead to adverse effects such as skin atrophy and telangiectasia, and could potentially mask symptoms of infection. This medication must be used precisely according to the type, location, and severity of the infection. Self-medication easily increases risks due to incorrect dosage or duration, which is why it is classified as a prescription drug and can only be purchased and used under a doctor's diagnosis and prescription.

Before applying the ointment, clean the affected area and ensure the skin is dry; avoid excessive contact of the medication with healthy skin. Strictly follow medical instructions regarding dosage and duration—do not increase the dose or extend usage time without authorization. Monitor skin reactions during treatment, and discontinue use immediately and seek medical advice if discomfort such as increased redness, swelling, or pain occurs. Keep the affected area well-ventilated, avoid friction or irritation, maintain a light diet to reduce skin stress, and support recovery.

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