What topical medication should be applied for a chancre?
Commonly used topical medications for chancres include benzathine penicillin ointment, erythromycin ointment, tetracycline ointment, mupirocin ointment, and fusidic acid cream. These should be used under a doctor's guidance according to the specific condition to avoid adverse reactions from self-medication. If skin lesions expand or other symptoms occur, prompt medical attention is necessary.
1. Benzathine Penicillin Ointment: Highly effective against *Treponema pallidum* (the causative agent of syphilis), this is a commonly used topical treatment for chancres. It acts directly on the lesion site to inhibit pathogen replication.
2. Erythromycin Ointment: A macrolide antibiotic effective against various pathogenic bacteria. Suitable for patients with chancres who are allergic to penicillin, it helps alleviate inflammatory responses in skin lesions.

3. Tetracycline Ointment: Broad-spectrum antibacterial properties that inhibit *Treponema pallidum* and some secondary bacterial infections. It can be applied locally to chancre lesions to assist in controlling infection.
4. Mupirocin Ointment: Possesses strong antibacterial activity, particularly effective against Gram-positive bacteria. Recommended for use when chancres are complicated by skin infections, helping to reduce secondary inflammation.
5. Fusidic Acid Cream: Inhibits a wide range of bacteria and can be used for local treatment of chancre lesions. It helps reduce symptoms such as redness, swelling, and ulceration, promoting wound healing.
Maintain cleanliness and dryness of the affected area. Avoid friction or scratching the lesion. Wear loose, breathable cotton clothing to minimize irritation. Follow a light, easily digestible diet rich in vitamins and protein. Maintain regular sleep patterns to strengthen immunity and support lesion recovery.