What medication works best for low-grade fever and sore throat?

Dec 01, 2025 Source: Cainiu Health
Dr. Ren Yi
Introduction
Medications that can be used for low-grade fever and sore throat include acetaminophen tablets, Lianhua Qingwen capsules, amoxicillin capsules, Lanqin oral liquid, and compound paracetamol and amantadine tablets. Acetaminophen tablets have antipyretic and analgesic effects, effectively reducing body temperature in cases of low-grade fever and simultaneously relieving the pain associated with sore throat. With a mild action and rapid onset, acetaminophen tablets are suitable for use when low-grade fever and sore throat occur together.

Under normal circumstances, medications that can be used for low-grade fever accompanied by sore throat include acetaminophen tablets, Lianhua Qingwen capsules, amoxicillin capsules, Lan Qin oral liquid, and compound paracetamol and amantadine tablets. Specific analysis is as follows:

1. Acetaminophen Tablets: These have antipyretic and analgesic effects, effectively reducing body temperature during low-grade fever and simultaneously relieving pain caused by sore throat. The effect is mild and rapid, making it suitable for cases where low-grade fever and sore throat occur together. It should be taken according to the recommended dosage to avoid overdose.

2. Lianhua Qingwen Capsules: A traditional Chinese medicine containing ingredients such as forsythia and honeysuckle, it functions to clear away epidemic toxins, relieve toxicity, promote lung function, and reduce heat. It not only alleviates symptoms of low-grade fever but also reduces discomforts like sore throat and dryness of the throat. It is suitable for low-grade fever and sore throat caused by wind-heat type colds and should be taken according to the instructions.

3. Amoxicillin Capsules: This is a penicillin-class antibiotic. If low-grade fever and sore throat are caused by bacterial infection—such as red and swollen throat with pus points—and there is no history of allergy, this medication may be used to inhibit bacterial growth and reduce inflammation. Dosage and duration of treatment must strictly follow medical advice.

4. Lan Qin Oral Liquid: Its main ingredients include isatis root (Ban Lan Gen) and skullcap (Huang Qin), which help clear heat and detoxify, soothe the throat, and reduce swelling. It is particularly effective in relieving sore throat symptoms and can also help alleviate general discomfort associated with low-grade fever. With its mild properties, it is suitable for people of all ages experiencing mild low-grade fever and sore throat.

5. Compound Paracetamol and Amantadine Tablets: Contains both antipyretic-analgesic and antiviral components. It helps lower body temperature during low-grade fever, relieve sore throat, and combat potential viral infections. It is ideal for early-stage colds accompanied by low-grade fever and sore throat. Avoid taking it concurrently with other antipyretic medications.

Before using any medication, examine the throat for signs of redness, swelling, or pus to preliminarily determine whether a bacterial infection is present. During treatment, drink plenty of warm water, ensure adequate rest, and avoid fatigue. If the low-grade fever persists for more than three days, sore throat worsens, or difficulty breathing occurs, seek medical attention promptly.

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