What causes a yellow mole?

Generally, yellow moles may result from factors such as genetic predisposition leading to pigment accumulation, ultraviolet (UV) radiation stimulating pigment production, pigmented polyposis syndrome, post-inflammatory hyperpigmentation, or endocrine disorders causing abnormal pigmentation. It is recommended to seek timely medical evaluation to identify the underlying cause and receive appropriate treatment under a doctor's guidance. Specific causes are analyzed as follows:

1. Genetic Predisposition Leading to Pigment Accumulation: Hereditary factors can cause abnormal distribution of skin pigment cells, resulting in localized clustering that forms yellow moles, typically appearing during childhood or adolescence. If the yellow mole shows no significant changes, special treatment is usually unnecessary. Regular monitoring of its size and color is advised, along with avoiding repeated friction or irritation. Wearing loose clothing can help minimize contact.

2. UV Radiation Stimulating Pigment Production: Prolonged sun exposure increases melanocyte activity, leading to pigment deposition and formation of yellow moles, commonly seen on exposed areas like the face and neck. Apply sunscreen with SPF 30+ when outdoors, wear wide-brimmed hats for sun protection, and avoid prolonged outdoor activities during peak sunlight hours. Existing yellow moles can be lightened with laser therapy.

3. Pigmented Polyposis Syndrome: An autosomal dominant genetic disorder characterized by yellow moles on the skin along with gastrointestinal polyps. The moles often appear around the lips, hands, and feet. Regular gastroenterological endoscopic screenings are necessary to monitor polyps. Follow medical advice to use medications such as mesalamine enteric-coated tablets, olsalazine sodium capsules, or celecoxib capsules. Endoscopic polypectomy should be performed if polyps become too large, to prevent malignant transformation.

4. Post-Inflammatory Hyperpigmentation: After resolution of skin inflammation such as eczema or dermatitis, yellowish-brown pigmented patches may remain, which are often mistaken for yellow moles. Avoid scratching inflamed areas. Use prescribed topical treatments such as hydroquinone cream, tretinoin cream, or azelaic acid cream. Additionally, apply moisturizers to restore the skin barrier and reduce further pigmentation.

5. Endocrine Disorders Causing Pigment Abnormalities: Hormonal fluctuations during pregnancy, menopause, or due to thyroid conditions can stimulate pigment deposition. Maintain regular sleep patterns and avoid staying up late; keep emotions stable. Under medical supervision, use hormonal regulators such as estradiol valerate tablets, progesterone capsules, or levothyroxine sodium tablets. Once hormone levels stabilize, the yellow moles may gradually fade.

In daily life, maintain clean skin using gentle skincare products to avoid irritating yellow moles. Eat more vitamin C-rich fruits and vegetables such as oranges and strawberries, which help inhibit pigment formation. Engage in regular physical activity to boost metabolism and support overall skin health.