What should I do if my face stings and turns red after using Apaduo gel?

Dec 01, 2025 Source: Cainiu Health
Dr. Liu Wenmin
Introduction
Stinging and redness of the face after using adapalene gel are common reactions, usually caused by drug irritation or skin intolerance. It is recommended to immediately discontinue the medication, gently cleanse the face, enhance moisturization and skin barrier repair, avoid irritating factors, and monitor changes in symptoms. If severe stinging, spreading redness and swelling, or peeling and blisters occur, prompt medical attention is advised.

Stinging and redness on the face after using adapalene gel require immediate discontinuation of the medication, gentle facial cleansing, enhanced moisturization and skin barrier repair, avoidance of irritating factors, and close monitoring of symptom changes. These reactions are commonly caused by drug-induced irritation or skin intolerance. If stinging is severe, redness spreads, or peeling, blisters occur, prompt medical attention is recommended.

1. Discontinue the medication immediately: Stop applying adapalene gel to prevent ongoing skin irritation and further damage from the active ingredients, allowing the skin an opportunity to begin self-repair.

2. Gentle facial cleansing: Use lukewarm water with a mild, non-irritating cleanser to gently remove any residual medication. Avoid vigorous rubbing to prevent additional damage to the skin barrier.

3. Enhance moisturization and repair: Apply a moisturizer or repair serum containing ingredients such as ceramides or squalane generously to the affected areas. This helps replenish moisture, restore the damaged skin barrier, and relieve discomfort.

4. Avoid irritating factors: Temporarily discontinue skincare products containing alcohol, fragrance, or alpha-hydroxy acids (AHAs). Avoid sun exposure, high temperatures, and scratching the face to minimize external irritation on sensitive skin.

5. Monitor symptom changes: Keep track of the extent, severity, and duration of redness and stinging. If symptoms gradually improve within 1–2 days, consider adjusting the application method later. Seek medical advice promptly if symptoms worsen.

When resuming use, start with low frequency and low concentration to build tolerance. Apply a thin layer once nightly, avoiding sensitive areas such as around the eyes and mouth. Maintain daily sun protection and use gentle moisturizing products to reduce the risk of irritation and steadily achieve therapeutic benefits.