How to treat blisters caused by flea bites
Generally, the main treatments for blisters caused by flea bites include local cleaning, environmental flea control, medication, physical relief, and traditional Chinese medicine (TCM) regulation. Specific details are as follows:

1. Local Cleaning
Flea saliva contains allergenic substances that trigger skin inflammation and blistering; cleaning helps reduce residual irritation. Gently rinse the affected area with running water or saline solution, avoiding rubbing the blister. After rinsing, pat dry with sterile gauze to keep the area clean and dry, preventing infection from rupture.
2. Environmental Flea Control
Fleas reproduce quickly and can repeatedly bite; thorough elimination is key to preventing re-injury. Soak clothes and bed sheets in boiling water before washing, then sun-dry to sterilize. Use a vacuum cleaner to clean corners of rooms and gaps in carpets, and apply approved flea-killing sprays on furniture and floors. Keep indoor areas well-ventilated and dry.
3. Medication
Medications can quickly relieve inflammation and itching, reducing the risk of blister rupture due to scratching. Patients may use calamine lotion, desonide cream, or cetirizine hydrochloride tablets as directed by a physician to alleviate symptoms.
4. Physical Relief
Cooling methods help soothe the skin, reducing itching and inflammatory responses. Wrap an ice pack in a clean towel and apply it to the affected area for 10–15 minutes at a time. Avoid direct contact between the ice pack and skin to prevent frostbite.
5. Traditional Chinese Medicine (TCM) Regulation
According to TCM, blisters after flea bites are associated with internal accumulation of dampness and heat, so treatment focuses on clearing heat and detoxifying. Honeysuckle dew may be applied externally as prescribed, or patients may take herbal formulas such as Lianqiao Baidu Pills or Fangfeng Tongsheng Pills under medical guidance. Spicy and stimulating foods should also be avoided to prevent aggravating damp-heat conditions.
In addition, scratching should be avoided during treatment. If a blister breaks accidentally, disinfect promptly with iodophor. Take protective measures when going outdoors and avoid places where fleas commonly thrive, such as grassy areas and locations with high pet density. Seek immediate medical attention if blisters spread extensively or if symptoms like fever occur.