Home
Articles
Q&A

Can hepatitis B with positive results for items 1, 3, and 4 heal spontaneously?

Dec 02, 2025 Source: Cainiu Health
Dr. Gao Jun
Introduction
In general, a positive result for hepatitis B markers 1, 3, and 4—namely, hepatitis B surface antigen (HBsAg), hepatitis B e antigen (HBeAg), and hepatitis B e antibody (anti-HBe)—requires comprehensive evaluation based on the stage of infection and individual immune status to determine the possibility of spontaneous recovery. Daily management should include a light diet, increased intake of high-quality protein and fresh fruits and vegetables, and strict abstinence from alcohol. It is important to maintain regular作息 (daily routines), avoid staying up late, and take medications as prescribed by a physician.

In general, a positive result for hepatitis B markers 1, 3, and 4—namely hepatitis B surface antigen (HBsAg), hepatitis B e antigen (HBeAg), and hepatitis B e antibody (anti-HBe)—requires comprehensive evaluation based on the stage of infection and the individual's immune status to determine the possibility of spontaneous recovery. The specific analysis is as follows:

During the early phase of acute infection, if the individual has a healthy immune system and low viral load, spontaneous recovery from the 1-3-4 positive pattern is possible. At this stage, the immune system is actively recognizing and eliminating the virus. The simultaneous positivity of these three markers may occur during the transition from HBeAg to anti-HBe. If HBsAg subsequently becomes negative and hepatitis B surface antibody (anti-HBs) develops, this indicates complete viral clearance and clinical recovery.

For patients with chronic hepatitis B or those with compromised immune function, in whom the infection has persisted for more than six months, the likelihood of spontaneous recovery from the 1-3-4 positive status is extremely low. The virus tends to integrate into hepatocytes, and the immune system is unable to fully eradicate it. Instead, repeated viral replication may lead to progressive liver damage.

Daily management should include a light diet rich in high-quality protein, fresh fruits, and vegetables, along with strict abstinence from alcohol. It is important to maintain regular sleep patterns, avoid staying up late, take prescribed medications as directed, and undergo regular follow-up tests for liver function and viral markers to monitor disease progression.

Related Articles

View All
Can short-acting interferon be used again after having been administered for 4 years and then discontinued for 4 years?
If the underlying disease (e.g., chronic hepatitis B or C) is currently in an active phase, with abnormal liver function or elevated viral load, and no severe baseline conditions (e.g., cirrhosis) have occurred during the 4-year period off treatment, the patient may be eligible for re-treatment—provided a physician evaluates them as having good overall tolerance and no contraindications to interferon use (such as severe cardiac or renal disease, or psychiatric history). An individualized dosing regimen would then be required.
avatar
Dr. Huang Yuhong
View Full Answer
After being scratched by a small hamster and receiving an injection, can I take fever-reducing medicine if I develop a fever?
If the fever exceeds 38.5°C, or is accompanied by significant discomfort such as headache, muscle aches, and fatigue, taking antipyretic medications (such as acetaminophen tablets or ibuprofen suspension) can help relieve symptoms and prevent potential adverse effects of high fever on the body. Antipyretics do not interact with vaccines administered after scratches or wounds, nor do they interfere with the vaccine's ability to induce an immune response; therefore, there is no need to worry about drug interactions.
avatar
Dr. Liu Wenmin
View Full Answer
Male: 1345 positive; Female: 25 positive. Is it contagious?
A positive result of 1345 in males indicates hepatitis B virus infection with active viral replication, typically associated with high viral load. The virus may be present in bodily fluids such as blood and semen, posing a risk of transmission to others through blood exposure or sexual contact. Even in the absence of obvious symptoms, the virus can still spread through close personal contact, so preventive measures should be taken seriously.
avatar
Dr. Huang Yuhong
View Full Answer
What is lymph node metastasis of liver cancer?
Under normal circumstances, lymph node metastasis of liver cancer may be caused by factors such as aging, chronic sleep deprivation, chronic hepatitis B, liver cirrhosis, and biliary tract infections. If discomfort symptoms occur, it is recommended to seek timely medical evaluation and treatment at a正规 hospital. In daily life, one should avoid staying up late and excessive fatigue; receive hepatitis B vaccination to prevent hepatitis B infection.
avatar
Dr. Gao Jun
View Full Answer
How many weeks should expectant fathers go for infectious disease screening?
The prospective father should undergo infectious disease screening 3–6 months before conception, including key tests for hepatitis B, hepatitis C, syphilis, and HIV. These screenings help detect infections early, prevent mother-to-child transmission during pregnancy, and protect the health of both mother and baby. If abnormal results are found, prompt medical consultation at a正规 hospital is necessary. Infectious disease screening during the preconception period is an essential step for achieving healthy pregnancy and optimal child development.
avatar
Dr. Li Feng
View Full Answer
How soon can I get tested for the four major infectious diseases after being pricked by a used needle?
Some infectious diseases have a window period, during which a positive result cannot be detected immediately after infection. For example, the window period for HIV is typically 2–4 weeks, and for hepatitis B it is about 1–6 months. If testing is performed immediately after exposure, a false-negative result may occur due to the ongoing window period, making it impossible to accurately determine whether infection has occurred. Therefore, retesting after the window period is recommended as advised by a physician.
avatar
Dr. Li Feng
View Full Answer
Can the remaining meat still be eaten if the part bitten by a mouse was cut off and the rest cooked?
There would be an extremely low possibility of safety only if the portion of meat bitten by a rat is very small, and the affected area along with a surrounding margin is immediately and thoroughly removed using clean tools, the remaining meat is then continuously cooked at temperatures above 100°C for sufficient time (e.g., the core temperature of the meat reaches above 75°C and is maintained for at least 30 seconds), and no contamination occurs during handling. However, this is still not recommended.
avatar
Dr. Huang Yuhong
View Full Answer
Can the antigen test detect the virus immediately after initial contact with a positive case?
If 2–3 days have passed after exposure (longer in some cases), the virus may have completed initial replication in the body, reaching a viral load detectable by antigen tests, and if the individual's immune system has not rapidly cleared the virus, the test may then yield a positive result. However, the exact time to detection varies among individuals and depends on the amount of viral exposure and the strength of the person's immune system.
avatar
Dr. Ren Yi
View Full Answer
彩牛养生

Your trusted source for health information and wellness guidance.

Quick Links

Resources

Connect

© 2024 HealthPortal. All rights reserved.