Several indicators must be positive for autoimmune hepatitis to confirm the diagnosis.

There is no fixed set of positive criteria for diagnosing autoimmune hepatitis. Diagnosis requires a comprehensive evaluation combining autoantibodies, liver function tests, imaging findings, and clinical presentation. The key diagnostic element is the presence of positive autoantibodies together with clear evidence of liver damage. Detailed analysis is as follows:

Autoantibodies serve as crucial clues. Commonly observed are positive antinuclear antibodies (ANA) and anti-smooth muscle antibodies (ASMA), although a single positive antibody result is insufficient for diagnosis. Liver function indicators must also be closely monitored—elevated transaminases and bilirubin levels indicate hepatocellular injury and constitute an essential basis for diagnosis. The specific types of positive antibodies and the degree of abnormal test results vary among individuals, so each case must be evaluated individually.

Other liver diseases such as viral hepatitis and drug-induced liver injury must be ruled out during diagnosis. Physicians will integrate the patient’s symptoms, medical history, and imaging results such as liver ultrasound to make a comprehensive assessment before confirming the diagnosis, thus avoiding misdiagnosis based solely on positive laboratory markers.

After diagnosis, patients should follow medical advice for standardized treatment. Maintain a light diet in daily life, avoid spicy and irritating foods, abstain from alcohol, keep a regular sleep schedule, avoid excessive fatigue, and undergo regular follow-up testing to support stable recovery of liver function.