How soon should a baby born to a hepatitis B-positive mother be tested for the five hepatitis B markers?

For babies born to mothers with hepatitis B, the hepatitis B panel test should be performed for the first time within 24 hours after birth, followed by re-examinations at 1 month and 6 months of age. Timely testing and standardized interventions can effectively determine infection status and assess the effectiveness of immunization. Specific details are as follows:

The first 24 hours after birth are a critical period. Testing during this time helps preliminarily determine whether intrauterine infection has occurred and provides a basis for subsequent preventive measures. At the same time, the newborn must immediately receive hepatitis B immune globulin (HBIG) and the first dose of the hepatitis B vaccine to establish dual protection. The test results from this phase, combined with proper immunization procedures, form an essential foundation for reducing infection risk and should not be delayed.

The re-examination at 1 month of age evaluates the initial response to the first vaccine dose, while the check-up at 6 months—after completion of the full vaccination series—is a key point for assessing whether sufficient protective antibodies have been produced. If antibody levels are inadequate or absent, additional vaccine doses should be administered under medical guidance to strengthen the immune protection and prevent future infection risks.

In daily life, ensure the child maintains a balanced diet, gets adequate sleep, and avoids excessive fatigue. Parents should practice personal protective measures, minimize risks during close contact, and adhere to regular monitoring to build a strong defense for the child's health.