Are there any serious side effects of molnupiravir?

Dec 02, 2025 Source: Cainiu Health
Dr. Li Feng
Introduction
In general, molnupiravir causes few severe side effects, and most people experience only mild reactions. However, individuals with allergies, impaired liver or kidney function, or those who misuse the drug may encounter potentially serious issues requiring caution. Before taking the medication, it is important to inform your doctor of any history of allergies or underlying medical conditions, and strictly follow medical advice regarding dosage and duration of treatment. Avoid alcohol during treatment and do not take other medications concurrently without medical guidance.

In general, molnupiravir rarely causes serious side effects, and most people experience only mild reactions after taking the medication. However, individuals with allergies or impaired liver or kidney function, as well as those who misuse the drug, may encounter potentially concerning conditions. A detailed analysis is as follows:

For most healthy individuals, mild reactions such as nausea, diarrhea, and headache may occur after taking molnupiravir. These symptoms are typically short-lived and resolve on their own. They do not impair bodily functions nor require treatment interruption. Adequate rest and a light diet during treatment can help alleviate discomfort.

Individuals with allergic predispositions may develop rashes or itching, and in severe cases may experience breathing difficulties. Patients with impaired liver or kidney function may face increased organ burden due to reduced metabolic capacity, potentially leading to abnormal test indicators. Taking the drug without following prescribed dosages or combining it with other medications may result in drug interactions and increase the risk of adverse effects.

Before starting treatment, patients should proactively inform their doctor about any history of allergies or underlying medical conditions, and strictly follow medical advice regarding dosage and duration of treatment. Alcohol consumption should be avoided during treatment, and no other medications should be taken concurrently without medical guidance.