Can Silibinin capsules be discontinued abruptly?

Dec 02, 2025 Source: Cainiu Health
Dr. Gao Jun
Introduction
In general, silibinin capsules should not be discontinued abruptly. Dosage adjustments should be made according to medical advice based on the patient's condition. Only after explicit evaluation by a physician can some patients with stable conditions gradually discontinue the medication as directed. Daily administration must strictly follow the prescribed dose and treatment duration; patients should not adjust the dosage or stop taking the medication based on subjective feelings. Liver function should be regularly monitored, bodily responses recorded, and any changes promptly reported to the physician.

Generally, Silibinin Capsules are not recommended to be discontinued abruptly. Dosage adjustments should be made according to medical advice based on the patient's condition. Only after a doctor's thorough evaluation may some patients with stable conditions gradually discontinue the medication under professional guidance. Detailed analysis is as follows:

Silibinin Capsules are commonly used to protect liver cells and improve liver function. After administration, the drug establishes a stable therapeutic effect in the body. Discontinuing the medication suddenly without medical supervision may interrupt the protective effect on liver cells, leading to fluctuations in liver function indicators. Particularly for patients with hepatitis or fatty liver disease, this could worsen pre-existing symptoms such as fatigue and loss of appetite, thereby negatively affecting treatment progress.

Discontinuation should only occur when follow-up examinations by a physician confirm consistently normal liver function, effective control of the underlying cause, and a clinical determination that continued medication is no longer necessary. For patients who experience intolerable side effects such as rash or nausea during treatment, dosage reduction followed by discontinuation should still be conducted under medical supervision, allowing the body to adjust gradually and avoiding discomfort associated with abrupt cessation.

Routine medication must be strictly taken according to the prescribed dose and duration. Patients should never adjust the dosage or stop taking the medication based on personal judgment. Regular liver function tests are essential, and any bodily responses should be documented and promptly reported to the physician.