What diseases does Entecavir tablet treat?

Entecavir tablets are primarily used to treat chronic hepatitis B virus infection, and are indicated for adult patients with active viral replication, persistently elevated serum alanine aminotransferase (ALT) levels, or histological evidence of active liver lesions. If chronic hepatitis B is confirmed, or symptoms such as fatigue and decreased appetite occur, it is recommended to seek timely medical evaluation to determine the need for treatment.

Entecavir is a guanine nucleoside analog that inhibits hepatitis B virus replication by blocking the activity of viral DNA polymerase, thereby reducing viral proliferation within hepatocytes. This helps alleviate liver inflammatory damage and delays disease progression to cirrhosis and hepatocellular carcinoma.

The drug is effective against both wild-type and certain drug-resistant mutant strains of hepatitis B virus. It is considered a first-line therapy in clinical practice for chronic hepatitis B and must be taken long-term and regularly to maintain antiviral efficacy. Discontinuing the medication without medical guidance may lead to viral rebound and worsening of the disease.

During treatment, the drug should be taken at a consistent time each day to avoid missed doses. A light, easily digestible diet is recommended, along with abstinence from alcohol and avoidance of high-fat foods. Patients should maintain regular sleep patterns and avoid staying up late. Regular monitoring of liver function and hepatitis B viral load is essential to ensure both treatment effectiveness and medication safety.