What diseases can the nine-valent vaccine prevent?
Dec 02, 2025
Source: Cainiu Health
Dr. Zhang Lu
Introduction
The 9-valent vaccine primarily prevents diseases associated with human papillomavirus (HPV) infection, including cervical cancer, vulvar cancer, vaginal cancer, anal cancer, and genital warts. It covers nine high-risk and low-risk HPV subtypes, offering broad protection. Individuals who are sexually active or have symptoms suggestive of related conditions should seek medical evaluation before vaccination.
The 9-valent vaccine primarily prevents diseases associated with human papillomavirus (HPV) infection, including cervical cancer, vulvar cancer, vaginal cancer, anal cancer, and genital warts. It offers protection against nine high-risk and low-risk HPV subtypes, providing broad-spectrum coverage. Individuals who are sexually active or experiencing symptoms suggestive of related conditions should seek medical evaluation promptly.
1. Cervical cancer: The vaccine targets HPV types 6, 11, 16, 18, 31, 33, 45, 52, and 58—these subtypes are the primary causes of cervical cancer. The vaccine stimulates the body to produce protective antibodies, reducing the risk of infection and subsequent malignant transformation.
2. Vulvar cancer: Most cases of vulvar cancer are linked to persistent infection with high-risk HPV types. By preventing infection from these specific subtypes, the 9-valent vaccine reduces the risk of vulvar mucosal lesions and helps protect vulvar health.
3. Vaginal cancer: HPV infection is a major contributing factor to vaginal cancer. The vaccine blocks the invasion of relevant HPV subtypes into the vaginal mucosa, lowering the likelihood of developing primary vaginal cancer, especially beneficial for young women.
4. Anal cancer: High-risk HPV infections are closely associated with the development of anal cancer. The vaccine prevents infection from the corresponding subtypes, reducing the risk of anal intraepithelial neoplasia and progression to cancer, and is suitable for both males and females.
5. Genital warts: These are primarily caused by HPV types 6 and 11. The 9-valent vaccine specifically prevents infection from these two low-risk subtypes, effectively reducing the incidence of genital warts such as condyloma acuminatum and minimizing transmission risk.
After vaccination, keep the injection site clean and avoid contact with water for 24 hours. Avoid strenuous exercise, maintain a light diet free of spicy or cold foods, follow a regular sleep schedule, and be aware of common local reactions such as mild redness, swelling, or pain at the injection site—these are normal and generally not a cause for concern.
