Is an AST/ALT ratio of 1.3 normal?

Generally, whether a AST/ALT ratio of 1.3 is normal depends on the individual values of the two enzymes. If both individual values are within the normal range, there is usually no concern; however, if either value is abnormal, it may indicate an underlying issue. If in doubt, it is advisable to consult a healthcare provider promptly. Detailed analysis is as follows:

If both aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels are within their normal reference ranges (e.g., AST 0–40 U/L, ALT 0–40 U/L), and only the AST/ALT ratio is 1.3, this situation is typically considered normal. A slightly elevated ratio may result from individual variation or testing variability and does not necessarily indicate liver damage, so excessive concern is unnecessary.

If AST alone is elevated (above the upper limit of normal) or ALT is significantly decreased, leading to an AST/ALT ratio of 1.3, this may suggest an abnormal condition. Elevated AST levels are commonly associated with liver injury, myocardial damage, or other conditions. Further evaluation—such as a complete liver function panel or abdominal ultrasound—is recommended to determine the underlying cause and prevent delays in diagnosis.

Upon finding an AST/ALT ratio of 1.3, first check the individual enzyme levels. If both are normal, periodic retesting is sufficient. If either value is abnormal, seek medical advice promptly and evaluate in combination with symptoms and other test results. In daily life, avoid alcohol consumption and staying up late to reduce liver strain and maintain stable liver function.