What does a positive EB virus RTA protein antibody mean?

Dec 02, 2025 Source: Cainiu Health
Dr. Li Feng
Introduction
A positive antibody test for Epstein-Barr virus (EBV) RTA protein indicates that the individual has been infected with EBV or is currently in an active infection phase. The RTA protein is a key protein associated with EBV replication, and detection of its antibody serves as an important diagnostic marker for EBV infection. If symptoms such as persistent fever, sore throat, or swollen lymph nodes are present, prompt medical evaluation is recommended.

Positive EB virus RTA protein antibody indicates that the body has been infected with EB virus or is currently in an infected state. RTA protein is a key protein associated with EB virus replication, and the presence of this antibody serves as an important diagnostic marker for EB virus infection. If accompanied by persistent fever, sore throat, swollen lymph nodes, or similar symptoms, prompt medical evaluation is recommended.

EB virus RTA protein antibodies are classified into two types: IgM and IgG. A positive IgM antibody typically suggests recent or acute infection, indicating that the body is in an active viral replication phase. A positive IgG antibody usually reflects past infection, meaning the body has developed immunity and is generally asymptomatic.

EB virus infection is common in the general population, and most infections are asymptomatic. After infection, the virus can remain latent in the body for a long time. Individuals with normal immune function can usually clear the virus spontaneously, while a minority may develop infectious mononucleosis. Those with compromised immunity should be vigilant about potential diseases caused by viral reactivation.

Maintain a regular作息 routine to enhance immunity, avoid excessive fatigue that may trigger viral reactivation, eat a balanced diet rich in vitamins and proteins, reduce intake of spicy and irritating foods, practice good personal hygiene to prevent cross-infection, and avoid undue anxiety—while staying attentive to regular follow-up testing.