What are the side effects of taking imatinib?

Imatinib is an anti-tumor medication. Side effects such as gastrointestinal discomfort, hematologic abnormalities, skin reactions, edema, and musculoskeletal pain may occur during treatment. Most side effects gradually subside as the body adapts to the drug; however, close monitoring of physical changes is necessary. Seek medical attention promptly if severe vomiting, persistent fever, or signs of bleeding occur.

1. Gastrointestinal discomfort: Common symptoms include nausea, vomiting, diarrhea, and abdominal pain, which typically appear early in treatment and are related to drug-induced irritation of the gastrointestinal mucosa. Symptoms can often be alleviated by adjusting the timing of medication intake or maintaining a light diet. Symptomatic management may be required in severe cases.

2. Hematologic abnormalities: Imatinib may cause reductions in white blood cells and platelets, increasing the risk of infection and bleeding. Regular blood tests are essential during treatment. Inform your doctor immediately if symptoms such as fatigue or gum bleeding occur.

3. Skin reactions: These may include rash, itching, and erythema, usually mild to moderate in severity. Avoid scratching to prevent further irritation. Antiallergic medications may be used under medical guidance when necessary. Discontinue the drug temporarily and seek medical evaluation if severe rash occurs.

4. Edema: Swelling of the eyelids or lower limbs is common and associated with the drug's effect on sodium and water metabolism. Reducing salt intake and engaging in moderate physical activity can help alleviate symptoms. Severe edema requires evaluation of cardiac and renal function.

5. Musculoskeletal pain: Muscle soreness and joint pain, especially in the limbs, may occur. Applying heat or performing gentle exercises may provide relief. Consult a physician if pain is severe to rule out other underlying conditions.

Imatinib must be taken strictly according to the prescribed dose and schedule—do not adjust the dosage without medical advice. Maintain a balanced diet rich in high-quality protein and vitamins, and avoid spicy or greasy foods. Follow a regular作息 (daily routine), avoid overexertion, keep the skin clean and dry, and engage in moderate exercise to strengthen overall health.