Could a millet-sized nodule at the apex of a lung lobe be tuberculosis?

Dec 02, 2025 Source: Cainiu Health
Dr. Ren Yi
Introduction
Miliary nodules appearing in the lung apices may indicate pulmonary tuberculosis, but they can also be caused by various other pulmonary diseases. A comprehensive evaluation based on specific symptoms, imaging characteristics, and laboratory tests is required. In daily life, avoid smoking and excessive alcohol consumption, refrain from inhaling dust and irritant gases, and maintain good indoor ventilation. Follow a light, nutritious diet with plenty of lung-moistening fruits and vegetables, and undergo regular follow-up pulmonary imaging examinations.

Pulmonary apical miliary nodules may indicate pulmonary tuberculosis, but they can also be caused by various other lung diseases. A comprehensive evaluation based on specific symptoms, imaging characteristics, and laboratory tests is required. The detailed analysis is as follows:

When pulmonary apical miliary nodules are accompanied by typical symptoms such as low-grade fever, night sweats, and hemoptysis, and imaging reveals uniformly distributed nodules, along with a positive tuberculin skin test and detection of Mycobacterium tuberculosis in sputum culture, a diagnosis of pulmonary tuberculosis can be established. In such cases, the nodules represent specific pathological changes resulting from Mycobacterium tuberculosis infection in the lungs, and prompt initiation of anti-tuberculosis treatment is necessary.

If the nodules are associated with symptoms like cough, sputum production, and chest pain, imaging shows uneven nodule sizes and ill-defined margins, tuberculosis-related tests are negative, and there is a history of other lung conditions such as pulmonary infection or pneumoconiosis, the nodules are more likely due to non-tuberculous causes.

In daily life, smoking and excessive alcohol consumption should be avoided. Inhalation of dust and irritant gases must be prevented, and indoor air circulation should be maintained. A light, nutritious diet rich in lung-nourishing fruits and vegetables is recommended. Regular follow-up pulmonary imaging is essential to closely monitor changes in the size and morphology of the nodules.