How long should you wait between vaccines before getting another one?

The interval between receiving different vaccines depends on the type of vaccine. Inactivated vaccines should generally be administered at least 14 days apart from other vaccines, while live attenuated vaccines require an interval of more than 28 days. However, in emergencies such as exposure to rabies, immediate vaccination can take precedence regardless of intervals. Detailed explanations are as follows:

Inactivated vaccines have high safety profiles. When co-administered with other inactivated or live attenuated vaccines, an interval of at least 14 days is sufficient. These vaccines do not cause pathogen replication; the main purpose of the interval is to differentiate potential local reactions, such as redness, swelling, or pain at the injection site. For example, spacing vaccines like the COVID-19 or influenza vaccine at least 14 days apart from hepatitis B or varicella vaccines helps reduce misinterpretation of adverse reactions.

Live attenuated vaccines contain weakened but live pathogens and require sufficient time for the body to develop an immune response. Therefore, an interval of more than 28 days is necessary between different live attenuated vaccines to prevent potential interference among them.

Before vaccination, individuals should proactively inform healthcare providers about their vaccination history and current health status. After vaccination, remain on-site for 30 minutes of observation. Upon returning home, keep the injection site clean and dry, avoid strenuous exercise, and complete all doses according to the recommended immunization schedule to ensure optimal protection.